Scientist

Company: Sanofi
Location: Framingham
Posted on: June 25, 2022

Job Description:

Position Overview/Department Description We are seeking an experienced upstream bioprocess development professional to join Cell Culture Development (CCD) as part of Medium & Bioprocess Technologies (CCD-MBT) at the Framingham, MA site as a Scientist. CCD-MBT is globally responsible for providing solutions to process challenges through the development and application of platform cell culture media and innovative technologies throughout CCD. The candidate will be self-motivated and strongly driven to succeed while demonstrating the ability to function well within a fast-paced, dynamic and collaborative team-oriented environment. The candidate will also be inquisitive and innovative, exhibiting scientific curiosity and the ability to acquire new skills while expanding the knowledge base of the organization.This individual will join a dynamic and motivated team charged with identifying process pain points and resolving the underlying problems, generating compelling data from relevant proof of concept studies, and designing novel process platforms in collaboration with Cell Culture Development colleagues. This is an exciting opportunity with the potential to have a significant impact on future process development and manufacturing strategies within the global Sanofi network.Key ResponsibilitiesDesign cell culture experiments using benchtop bioreactors, high throughput cell culture methods, and/or pilot scale single-use bioreactorsIndependently plan and conduct complex experiments on multiple projects and suggest improvements and solutions to address new problems as they occurSupport development of in-house cell culture media for fed-batch and perfusion processesPromote mechanistic understanding of key factors and associated metabolic pathways relating to cell culture medium and process developmentPerform data analysis and prepare and review technical reports, SOPs, and internal presentationsDevelop, maintain and demonstrate knowledge of concepts, principles, and techniques in upstream bioprocess manufacturingDemonstrate insights on important new findings in published literature, prepare manuscripts for relevant bioprocess journals, and present to industry leaders at national/international conferencesFoster effective communications between upstream bioprocess teamsEnsure the highest standards of safety and environmental compliance are maintained in the workplaceBasic QualificationsPhD in Chemical Engineering, Biochemical Engineering, Cell Biology, Biochemistry or a related discipline or Master's degree with a minimum of 4 years of relevant industry experience, or Bachelor's degree with a minimum of 6 years of relevant industry experienceExperience in mammalian cell culture process developmentExcellent organizational, interpersonal, communication and problem-solving skillsPreferred QualificationsExperience with fed-batch and perfusion-based cell culture processes and bioreactor systems at various scalesKnowledge of concepts and techniques for the development of high-performing CHO cell culture media and feedsExperience with Design of Experiments (DOE) methodology for process development and characterization and related process data analysisUnderstanding of high throughput cell culture systems and related automated liquid handling technologiesExperience with hands-on operation and troubleshooting of LC-MS instrumentsExperience with MS-based metabolomic approaches and methods for targeted and untargeted analyticsAt Sanofi R&D North America, we deliver meaningful solutions for patients. We transform science into breakthrough, best-in-class and first-in-class medicines and vaccines. We believe in creating a diverse and inclusive workforce - and workplace - which brings together the collective brainpower of over 2,000 colleagues and provides you with an exciting place to grow and develop. We set the bar high, and we deliver. Join us and together we will build on our trusted legacy of breakthroughs for society.As a healthcare company and a vaccine manufacturer, Sanofi has an important responsibility to protect individual and public health. This position will require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities.Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.GD-SALI-SAPDNAt Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.PDN-95c8336c-16fa-4684-8170-6127396dc027

Keywords: Sanofi, Framingham , Scientist, Other , Framingham, Massachusetts