Scientist CMC Developability & Preformulation Sciences
Company: Sanofi
Location: Framingham
Posted on: June 25, 2022
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Job Description:
Job Responsibilities:We are seeking a highly motivated and
talented Scientist to join our Developability & Preformulation
Sciences (DPFS) group.DPFS is part of the global Biologics Drug
Product Development and Manufacturing (BioDPD&M) organization,
a critical R&D function enabling the manufacturing of stable
and deliverable dosage forms along the complete development
timeline from molecule selection to commercial tech transfer.Be
part of a team with global responsibility for enabling candidate
selection within Sanofi's promising pipeline of biotherapeutics and
for determining the formulation design space for a variety of
biotherapeutic modalities.Help chart the roadmap to continuously
improving capabilities in the prediction, characterization, and
control of the molecular liabilities that limit the development of
stable and manufacturable drugs.Serve as a team and technical
leader in BioDPD&M, where you will act as a critical
facilitator of the Research-to-Development transition and play an
important role in laying the foundation for successful commercial
formulations.Be responsible for planning and executing
developability assessments and preformulation workflows,
collaborating with colleagues in discovery, protein engineering,
analytics, drug substance process development, and project
management.Design and lead laboratory research focused in the areas
of therapeutic candidate credentialing technologies,
characterization of protein solution properties, and the molecular
basis of high concentration behaviors.Basic Qualifications:PhD in
Biochemistry or a related discipline or a Master's degree with a
minimum of 4 years of relevant laboratory experience or a
Bachelor's degree with a minimum of 6 years of experienceKnowledge
of proteins (antibody and AAV caspid is preferred)Broad working
knowledge of biochemical and biophysical characterization methods
such as chromatography, CE-SDS, gel electrophoresis and western
blotting, UV/CD/fluorescence spectroscopies, calorimetry, light
scattering, and sedimentationStrong work ethic, team- and
project-focused, and motivated to produce high quality data on an
aggressive timeline.Solid understanding of protein structure,
chemistry, and degradation mechanismsGood leadership qualities and
an established track record of cross-functional project
managementPreferred Qualifications:Good communication and
presentation skillsKnowledge of the fundamental biopharmaceutical
principles of developing injectable biologic drug products.iLab
experience is highly desirable.Experience with AAVs to support drug
product development of a gene therapy program.Pursue progress,
discover extraordinaryBetter is out there. Better medications,
better outcomes, better science. But progress doesn't happen
without people - people from different backgrounds, in different
locations, doing different roles, all united by one thing: a desire
to make miracles happen. So, let's be those people.At Sanofi, we
provide equal opportunities to all regardless of race, colour,
ancestry, religion, sex, national origin, sexual orientation, age,
citizenship, marital status, disability, or gender identity. Watch
our ALL IN video and check out our Diversity Equity and Inclusion
actions at sanofi.comAt Sanofi R&D North America, we deliver
meaningful solutions for patients. We transform science into
breakthrough, best-in-class and first-in-class medicines and
vaccines. We believe in creating a diverse and inclusive workforce
- and workplace - which brings together the collective brainpower
of over 2,000 colleagues and provides you with an exciting place to
grow and develop. We set the bar high, and we deliver. Join us and
together we will build on our trusted legacy of breakthroughs for
society.Sanofi Inc. and its U.S. affiliates are Equal Opportunity
and Affirmative Action employers committed to a culturally diverse
workforce. All qualified applicants will receive consideration for
employment without regard to race; color; creed; religion; national
origin; age; ancestry; nationality; marital, domestic partnership
or civil union status; sex, gender, gender identity or expression;
affectional or sexual orientation; disability; veteran or military
status or liability for military status; domestic violence victim
status; atypical cellular or blood trait; genetic information
(including the refusal to submit to genetic testing) or any other
characteristic protected by law.As a healthcare company and a
vaccine manufacturer, Sanofi has an important responsibility to
protect individual and public health. All US based roles require
individuals to be fully vaccinated against COVID-19 as part of your
job responsibilities.Fully vaccinated, according to the CDC, an
individual is considered to be "fully vaccinated" fourteen (14)
days after receiving (a) the second dose of the Moderna or Pfizer
vaccine, or (b) the single dose of the J&J vaccine. Fully
vaccinated, for new Sanofi employees, is to be fully vaccinated 14
DAYS PRIOR TO START DATE. GD-SALI-SAPDNAt Sanofi diversity and
inclusion is foundational to how we operate and embedded in our
Core Values. We recognize to truly tap into the richness diversity
brings we must lead with inclusion and have a workplace where those
differences can thrive and be leveraged to empower the lives of our
colleagues, patients and customers. We respect and celebrate the
diversity of our people, their backgrounds and experiences and
provide equal opportunity for
all.PDN-96008640-87f8-4f67-b710-1617ee577f60
Keywords: Sanofi, Framingham , Scientist CMC Developability & Preformulation Sciences, Other , Framingham, Massachusetts
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