Principal Research Associate Protein Pre-Formulation

Company: Sanofi
Location: Framingham
Posted on: June 25, 2022

Job Description:

Position/Department Overview:We are seeking a highly motivated and talented Principal Research Associate to join our Developability & Preformulation Sciences (DPFS) group.DPFS is part of the global Biologics Drug Product Development organization, a critical R&D function enabling the manufacturing of stable and deliverable dosage forms along the complete development timeline from molecule selection to commercial tech transfer.Key Responsibilities:Part of a team with global responsibility for enabling candidate selection within Sanofi's promising pipeline of biotherapeutics, for determining the formulation space for a variety of biotherapeutic modalities, and for charting the roadmap to continuously improving capabilities in the prediction, characterization, and control of the molecular liabilities that limit the development of stable and manufacturable drugsTimely execution of laboratory studies in support of developability assessments and preformulation workflowsSupport research activities focused in the areas of therapeutic candidate credentialing technologies, characterization of protein solution properties, and the molecular basis of high concentration behaviors.Basic Qualifications:Bachelor's degree in Biochemistry or a related discipline with a minimum of 4 years of relevant laboratory experience or a Master's degree with a minimum of 2 years of relevant laboratory experience.Good work ethic, be team- and project-focused, and be motivated to produce high quality data on an aggressive timelineSolid understanding of protein structure, chemistry, and degradation mechanismsPreferred Qualifications:Excellent communication and presentation skillsWorking knowledge of the fundamental biopharmaceutical principles of developing injectable biologic drug productsPractical experience with biochemical and biophysical characterization methods such as chromatography, electrophoresis, UV/CD/fluorescence spectroscopies, calorimetry, light scattering, and sedimentationAt Sanofi R&D North America, we deliver meaningful solutions for patients. We transform science into breakthrough, best-in-class and first-in-class medicines and vaccines. We believe in creating a diverse and inclusive workforce - and workplace - which brings together the collective brainpower of over 2,000 colleagues and provides you with an exciting place to grow and develop. We set the bar high, and we deliver. Join us and together we will build on our trusted legacy of breakthroughs for society.Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.As a healthcare company and a vaccine manufacturer, Sanofi has an important responsibility to protect individual and public health. All US based roles require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities.According to the CDC, an individual is considered to be "fully vaccinated" fourteen (14) days after receiving (a) the second dose of the Moderna or Pfizer vaccine, or (b) the single dose of the J&J vaccine. Fully vaccinated, for new Sanofi employees, is to be fully vaccinated 14 DAYS PRIOR TO START DATE. GD-SALI-SAPDNAt Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.PDN-964afd39-e916-4682-a7eb-e3b6c9544caa

Keywords: Sanofi, Framingham , Principal Research Associate Protein Pre-Formulation, Other , Framingham, Massachusetts