Senior Research Associate I, Global Biologics

Company: Takeda Pharmaceutical
Location: Framingham
Posted on: May 12, 2022

Job Description:

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Job Description
About the role: At Takeda, we are a forward-looking, world-class R&D organization that unlocks innovation and delivers transformative therapies to patients. By focusing R&D efforts on four therapeutic areas and other targeted investments, we push the boundaries of what is possible in order to bring life-changing therapies to patients worldwide.

Join Takeda as a Senior Research Associate I where you will maintain the Takeda Global Bank. You will also maintain and expand the cell repository that will include ordering new cell lines, routine scale-up of cultures, sample preparation for QC experiments (mycoplasma, MAP, C.Bovis, and STR test), distribution of the banked cells/vials across the organization, and characterization of new cell lines. As part of the Therapeutic Generation and Screening team, you will report to the Manager II and work with the Global Biologics organization.

How you will contribute: M aintain and expand the cell repository that will include ordering new cell lines, routine scale-up of cultures, sample preparation for QC experiments (mycoplasma, MAP, C.Bovis, and STR test), distribution of the banked cells/vials across the organization, and characterization of new cell lines.
Evaluate compound effects on cell viability and analyzing a variety of cell signaling pathway markers.
Show willingness, adaptability, and capability to perform multi-task and experience of large-scale sample management.
Work with lab management, facilities, Lab Operations, Discovery Operations, CROs and EHS, communicate and coordinate cell bank and tissue culture-related activities.
Have a wide range of immuno-oncology, molecular, and cellular biology techniques including mammalian cell culture, cell-based proliferation/viability assays.
Manage the preparation, filling in weekly cell requests, tracking cell banks for release testing and stability testing, authoring SOPs, technical reports, CoAs, and regulatory documents.
Prepare and track test samples for QC experiments (mycoplasma, STR, cell viability test, etc.).
Excellent analytical, organizational, and communication skills are essential.

Minimum Requirements/Qualifications: Master's degree in cell immunology, protein/antibody science, molecular biology, and/or > 1 years equivalent relevant work experience with strong knowledge of cell biology, immuno-oncology, and cell therapy.
Bachelor's degree with > 3 years relevant experience.
Extensive experience in mammalian cells culture, including the application of aseptic techniques for media compounding, passaging, maintenance, and cryopreservation of cell cultures.
Strong organization skills, and a track record of large-scale sample management. Proficient in analyzing scientific datasets and have experience with electronic document management systems, cell bank work presentation, and troubleshooting.
Basic immuno-oncology, cancer biology skills are required, advanced skills are highly desired.
Experience in a cGMP environment and knowledge of large-scale cell culture and media preparation would be preferred.
Capable of working independently to solve scientific questions.
Dedication to working in a team-oriented environment to contribute to shared projects.
Effectively coordinate with other research teams.

What Takeda can offer you: Comprehensive Healthcare: Medical, Dental, and Vision
Financial Planning & Stability: 401(k) with company match and Annual Retirement Contribution Plan
Health & Wellness programs including onsite flu shots and health screenings
Generous time off for vacation and the option to purchase additional vacation days
Community Outreach Programs and company match of charitable contributions
Family Planning Support
Flexible Work Paths
Tuition reimbursement

More about us: At Takeda, we are transforming patient care through the development of novel specialty pharmaceuticals and best in class patient support programs. Takeda is a patient-focused company that will inspire and empower you to grow through life-changing work.

Certified as a Global Top Employer, Takeda offers stimulating careers, encourages innovation, and strives for excellence in everything we do. We foster an inclusive, collaborative workplace, in which our teams are united by an unwavering commitment to deliver Better Health and a Brighter Future to people around the world.

Takeda U.S. Vaccine Requirement:
Absent an approved religious or medical reason, all US office-based and lab-based Takeda employees who work fully on-site or in a hybrid model (as determined by Takeda) must be fully vaccinated to work at a Takeda site or to engage with Takeda colleagues or anyone else on behalf of Takeda. US field-based employees must be fully vaccinated as a condition of employment, absent an approved religious or medical reason. US employees who work at a Takeda manufacturing facility, and those who work at a BioLife center or BioLife lab, may be subject to different guidelines. If you are contacted by a Takeda recruiter about your job application, we encourage you to seek more information on the applicable guidelines for the Business Unit/Function to which you have applied.

In accordance with the CO Equal Pay Act, Colorado Applicants Are Not Permitted to Apply.

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EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations
USA - MA - Cambridge

Worker Type
Employee
Worker Sub-Type
Regular
Time Type
Full time

Keywords: Takeda Pharmaceutical, Framingham , Senior Research Associate I, Global Biologics, Other , Framingham, Massachusetts