Principal Research Associate Bioprocess Analytics

Company: Sanofi
Location: Framingham
Posted on: May 10, 2022

Job Description:

This position resides within the BioProcess Analytics group which is part of the Global CMC Development organization at Sanofi, Framingham, MA. The candidate will be part of a multi-disciplinary team providing analytical support to a strong pipeline of R&D programs within Sanofi during early and late stage process development.We are looking for a skilled, highly motivated individual with expertise in biology/biochemistry who works well in a team-setting to meet project and development goals within established timelines. The Principal Research Associate will be part of a multi-disciplinary team focused on multiple projects to support development and optimization of novel analytical methods, including some routine testing, for R&D programs within Sanofi. The ideal candidate is required to have significant industry experience with analysis and characterization of biologic therapeutic protein products using a variety of analytical methods and capable of mentoring more junior members of the team.Key Responsibilities:Support development of cutting-edge technologies and analytical method platforms such as ELISA and other binding assays, impurity assays (e.g. residual DNA, Host Cell Protein) as well as other novel techniquesProvide analytical testing support in a variety of testing platforms, in a non-GMP setting, supporting R&D Biologics Development.Manage work assignments, analyze and interpret test results, and conduct necessary troubleshooting under the supervision of the manager.Write technical reports, study protocols, and results and effectively communicate progress and results with the team.Provide training and lab supervision of junior analysts and additional operators in analytical methods transfer, implementation, execution and documentation.Maintain good communication and collaboration with internal colleagues.Basic QualificationsMaster's degree in Biology, Biochemistry or related discipline with a minimum of 2 years of relevant industry experience or Bachelor's degree with a minimum of 4 years of relevant industry experience.Hands-on experience including but not limited to nucleic acid extraction, qPCR and ELISA-based immunoassays.Hands-on experience in data processing software such as Softmax, AccuSEQ, and QuantStudio.Knowledge of GxPs, ICH/USP guidelines, regulations and procedures.Experience working independently with multidisciplinary teams in a matrix environment.Well-organized, strong scientific curiosity, self-motivated, hard-working and detail-oriented individual able to work successfully in both a team/matrix environment as well as independently.Industrial experience working in a biotechnology/pharmaceutical company with a sound understanding of protein therapeutic process development.Excellent written and oral communication skills.Preferred Qualifications:Strong technical background in qPCR, ELISA and/or other binding assays.Assay development and qualification in a non-GMP setting.Experience in automated liquid handling a plus.Experience in HPLC/UPLC, CE-SDS and/or cIEF would be beneficial for the position.At Sanofi R&D North America, we deliver meaningful solutions for patients. We transform science into breakthrough, best-in-class and first-in-class medicines and vaccines. We believe in creating a diverse and inclusive workforce - and workplace - which brings together the collective brainpower of over 2,000 colleagues and provides you with an exciting place to grow and develop. We set the bar high, and we deliver. Join us and together we will build on our trusted legacy of breakthroughs for society.Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.As a healthcare company and a vaccine manufacturer, Sanofi has an important responsibility to protect individual and public health. All US based roles require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities.Fully vaccinated, according to the CDC, an individual is considered to be "fully vaccinated" fourteen (14) days after receiving (a) the second dose of the Moderna or Pfizer vaccine, or (b) the single dose of the J&J vaccine. Fully vaccinated, for new Sanofi employees, is to be fully vaccinated 14 DAYS PRIOR TO START DATE. GD-SALI-SAPDNAt Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.PDN-95f67678-5319-4bd9-8c70-0bb88aee2578

Keywords: Sanofi, Framingham , Principal Research Associate Bioprocess Analytics, Other , Framingham, Massachusetts