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Scientist II

Company: Sanofi
Location: Framingham
Posted on: May 9, 2022

Job Description:

--- Work with a global group of engineers and scientists to develop robust and scalable downstream processes for monoclonal antibodies, bispecific antibodies, Fc-, Fab-, and fusion proteins, enzymes, and other recombinant proteins to support GMP manufacture.
Work may include some of the following.--- Work on MSAT development and pilot-scale projects, to include regular team meetings and updates for, data management, investigations, technical report writing and regulatory filings.--- Support virus clearance studies to support regulatory filings--- Support of scale-down model development and qualification--- Support technology transfer including projects for internal and external partners.--- Support DOE studies to establish proven and acceptable process ranges.EDUCATION / REQUIREMENTSRequirementsM.S./M.A. in Chemical Engineering, or related field, with 0 to 3+ years of relevant experience;or B.S./B.A. in Chemical Engineering, or related field, with 0- 5+ years of relevant experience.
Ideally experience in some of the areas listed below--- Experience with Protein Purification and the with automated chromatography platforms (e.g. GE Healthcare AKTA)--- Experience with authoring and executing protocols, interpretation of data and generating final reports--- Process-scale chromatography and filtration including nano, tangential flow, and normal flow filtration--- Experience writing and revising standard operating procedures and batch production records--- Experience with operating and troubleshooting process equipment

Keywords: Sanofi, Framingham , Scientist II, Other , Framingham, Massachusetts

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