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Postdoctoral Fellow, Genomic Medicine Unit and Rare Neurological Diseases

Company: Principia Biopharma Inc.
Location: Framingham
Posted on: June 4, 2021

Job Description:

Position Overview:

Sanofi's Genomic Medicine Unit based in Framingham MA is looking for a highly qualified and motivated Postdoctoral Scientist to help develop novel therapies for the treatment of amyotrophic lateral sclerosis (ALS). The successful candidate will work closely with scientists in the Rare Neurological Disease cluster to characterize rodent models of ALS to validate therapeutic targets and to understand disease biology. Experience with rodent behavioral testing, stereotaxic surgery, tissue collection, immunohistochemistry, RNA scope, and molecular biology techniques is highly desired.

Key Responsibilities:

* Characterize rat and mouse models of ALS using behavioral, biochemical and histological assays.

* Perform stereotaxic surgery or IV injections to delivery experimental treatments.

* Implement multiple state-of-the-art techniques in molecular biology, biochemistry, and microscopy.

* Work with cross functional teams to use omics, bioinformatics, data mining and other approaches to validate and identify targets.

* Analyze, interpret, and present experimental results at lab meetings.

* Publish/present findings in peer-reviewed journals/scientific conferences.

* Maintain accurate records of experiments and analyses.

* Maintain lucid and effective communication with manager and other colleagues.

Basic Qualifications:

* Ph.D. in Neuroscience or related field, with at 0-2 years of postdoctoral training.

* Previous first-author publication(s) in internationally recognized journals are required.

* Ability to meet aggressive timelines and deliverables in a collaborative environment.

* Excellent speaking, reading and writing skills.

* Strong analytical and organizational skills.

* Curiosity and a willingness to work independently.

* Must have permanent US work authorization

Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.

#GD-SA

#LI-SA

At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

Keywords: Principia Biopharma Inc., Framingham , Postdoctoral Fellow, Genomic Medicine Unit and Rare Neurological Diseases, Other , Framingham, Massachusetts

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