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Scientist, Process Analytical Technology

Company: Sanofi
Location: Framingham
Posted on: May 9, 2022

Job Description:

Position Overview:Sanofi seeks a talented Scientist to join our Process Analytical Technology (PAT) Development team, part of the Global CMC Development organization of Sanofi R&D. This individual will join a motivated team and serve as a key technical expert in applying PAT tools such as vibrational spectroscopy (Raman, FTIR, NIR) and other analyzers (e.g., sensors, UPLC) for real-time analytics and process control in support of early- to late-stage bioprocess development.Key Responsibilities: Hands-on development and deployment of Raman-based PAT methods and other in-line and on-line PAT tools to monitor and control Process Parameters and Product Quality Attributes for therapeutic proteins.Perform data analysis using spectroscopy instruments and other analyzers (e.g., smart sensors, micro-Chips, UPLC/HPLC, etc.).Interpret spectral data; manage and align process and analytical data sets.Apply chemometric methods for multivariate data analysis, responsible for model generation, validation, and maintenance.Compile and communicate complex datasets to facilitate informed decision-making; summarize the results in concise technical reports and presentations.Identify process development PAT opportunities: work with process engineers to evaluate new PAT techniques to improve process understandingBasic Qualifications:Ph.D. Degree in Chemical Engineering, Biochemical Engineering, Biochemistry, Analytical Chemistry, or related discipline, or Master's Degree with a minimum of 4 years of relevant industry experience or Bachelor's Degree with a minimum of 6 years of relevant industry experience.Understanding of Vibrational Spectroscopy (Raman, FTIR, NIR, etc.), spectra interpretation, and analysis.Good knowledge of data-driven qualitative and quantitative chemometric model building approachesAbility to work independently in a multidisciplinary and team environment. Excellent organizational, communication and problem-solving skills.Self-motivated, strongly driven to succeed and inquisitive.Preferred Qualifications:Proficient in data-driven qualitative and quantitative chemometric model building approaches, machine learning skills is a plus. Hands-on experience using multivariate software platforms such MATLAB, SIMCA, Unscrambler for data analysis and programming skills (Python, R, etc.) Strong technical aptitude for the development, integration, and implementation of novel process analytical technology.At Sanofi R&D North America, we deliver meaningful solutions for patients. We transform science into breakthrough, best-in-class and first-in-class medicines and vaccines. We believe in creating a diverse and inclusive workforce - and workplace - which brings together the collective brainpower of over 2,000 colleagues and provides you with an exciting place to grow and develop. We set the bar high, and we deliver. Join us and together we will build on our trusted legacy of breakthroughs for society.As a healthcare company and a vaccine manufacturer, Sanofi has an important responsibility to protect individual and public health.This position will require individuals to be fully vaccinated against COVID-19 as part of your job responsibilities.Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law.GD-SALI-SAPDNAt Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.PDN-950f1d39-b53d-471a-bc35-87941a79b6ee

Keywords: Sanofi, Framingham , Scientist, Process Analytical Technology, IT / Software / Systems , Framingham, Massachusetts

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