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Laboratory Technician I

Company: Aequor Technologies LLC
Location: Framingham
Posted on: January 25, 2023

Job Description:

Start Date: As soon as possible
Onsite Position
Job Overview:
The Laboratory Technician in Drug Substance MSAT Downstream will work in a matrix team environment with global engineers and scientists to achieve robust and scalable purification processes to support 2nd generation processes, late-stage programs, and life-cycle management. This position will support the development of purification and drug substance storage processes for a wide variety of molecules and modalities.

In concert with ***'s Patient First philosophy, this role work in a laboratory team developing robust and scalable protein purification processes to deliver to the manufacturing group. As part of the MSAT group this position will also support the manufacturing team to ensure the successful technical transfers to produce pharmaceutical drugs for life saving therapies.

Responsibilities:
" Work with a global group of engineers and scientists to develop robust and scalable downstream processes, as well as frozen and liquid drug substance storage processes, for monoclonal antibodies, bispecific antibodies, Fc-, Fab-, and fusion proteins, enzymes, and other recombinant proteins to support GMP manufacture.
" Work on MSAT development and pilot-scale projects, to include regular team meetings and updates for, data management, investigations, technical report writing and regulatory filings.
" Support technology transfer including projects for internal and external partners.
" Support DOE studies to establish proven and acceptable process ranges.
" Author internal procedures and technical reports.

Basic Qualifications:
" B.S./B.A. in Chemical Engineering, Biotechnology, or related discipline, with 0 to 2 years of relevant experience.

Preferred Qualifications:
" Experience in a biotechnology or pharmaceutical industry laboratory setting
" Experience with downstream processes at lab, pilot, or production scale including chromatography (e.g. AKTA), tangential flow filtration, or nanofiltration
" Knowledge in protein stability studies and routine protein analytical techniques
" Strong technical writing and presentation skills
" Experience with statistical analysis software

Keywords: Aequor Technologies LLC, Framingham , Laboratory Technician I, Healthcare , Framingham, Massachusetts

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