Laboratory Technician I
Company: Aequor Technologies LLC
Posted on: January 25, 2023
Start Date: As soon as possible
The Laboratory Technician in Drug Substance MSAT Downstream will
work in a matrix team environment with global engineers and
scientists to achieve robust and scalable purification processes to
support 2nd generation processes, late-stage programs, and
life-cycle management. This position will support the development
of purification and drug substance storage processes for a wide
variety of molecules and modalities.
In concert with ***'s Patient First philosophy, this role work in a
laboratory team developing robust and scalable protein purification
processes to deliver to the manufacturing group. As part of the
MSAT group this position will also support the manufacturing team
to ensure the successful technical transfers to produce
pharmaceutical drugs for life saving therapies.
" Work with a global group of engineers and scientists to develop
robust and scalable downstream processes, as well as frozen and
liquid drug substance storage processes, for monoclonal antibodies,
bispecific antibodies, Fc-, Fab-, and fusion proteins, enzymes, and
other recombinant proteins to support GMP manufacture.
" Work on MSAT development and pilot-scale projects, to include
regular team meetings and updates for, data management,
investigations, technical report writing and regulatory
" Support technology transfer including projects for internal and
" Support DOE studies to establish proven and acceptable process
" Author internal procedures and technical reports.
" B.S./B.A. in Chemical Engineering, Biotechnology, or related
discipline, with 0 to 2 years of relevant experience.
" Experience in a biotechnology or pharmaceutical industry
" Experience with downstream processes at lab, pilot, or production
scale including chromatography (e.g. AKTA), tangential flow
filtration, or nanofiltration
" Knowledge in protein stability studies and routine protein
" Strong technical writing and presentation skills
" Experience with statistical analysis software
Keywords: Aequor Technologies LLC, Framingham , Laboratory Technician I, Healthcare , Framingham, Massachusetts
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