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Research Associate, Genomic Medicine Bioanalytics

Company: Principia Biopharma Inc.
Location: Framingham
Posted on: April 10, 2021

Job Description:

Position Overview/Department Description We are seeking an energetic and highly motivated Research Associate to join the newly formed Analytical Development and QC group within the Genomic Medicine Unit (GMU), located in Framingham, MA. The GMU Analytical Development group has the overall responsibility to establish phase appropriate control strategies and to develop, qualify, and validate robust analytical methods to support release and characterization testing of different gene therapy candidates. In addition, the group supports cGMP-compliant release and stability testing of clinical supplies performing both the product-specific as well as compendial methods. The primary accountability is to perform GMP testing, develop and validate physicochemical methods as well as perform compendial method verifications to enable rapid progression of various early stage gene therapy candidates into the clinic. Key Responsibilities * Develop, qualify and transfer analytical methods to support drug substance and drug product release and stability testing. * Perform method development and scientific procedures with support from group SMEs and leaders. * Plan and prioritize concurrent experimental procedures and document in an electronic lab notebook. Integrate, compile, analyze, and interpret data with some supervision. * Perform cGMP sample testing, following method protocols (SOPs), and generate data packets for results. * Author SOPs and technical reports and provide oral presentations on results. * Ensure timely completion and delivery of analytical results and documentation (ELN, technical reports, SOPs, etc.). Basic Qualifications * Bachelor's Degree in a relevant discipline * Basic understanding of physicochemical methods e.g. SDS-PAGE, CE, HPLC, GC, CE, mass spectrometry. * Excellent communication skills Preferred Qualifications * Intern or co-op experience working in a laboratory environment. * Experience with physiochemical techniques such as SDS-PAGE, CE, HPLC, GC, CE or mass spectrometry. Sanofi Inc. and its U.S. affiliates are Equal Opportunity and Affirmative Action employers committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status; domestic violence victim status; atypical cellular or blood trait; genetic information (including the refusal to submit to genetic testing) or any other characteristic protected by law. #GD-SA #LI-SA At Sanofi diversity and inclusion is foundational to how we operate and embedded in our Core Values. We recognize to truly tap into the richness diversity brings we must lead with inclusion and have a workplace where those differences can thrive and be leveraged to empower the lives of our colleagues, patients and customers. We respect and celebrate the diversity of our people, their backgrounds and experiences and provide equal opportunity for all.

Keywords: Principia Biopharma Inc., Framingham , Research Associate, Genomic Medicine Bioanalytics, Healthcare , Framingham, Massachusetts

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